1st International and 10th National Iranian Conference on Bioinformatics
Home Accepted Papers
The development of natural dietary supplements and medicines utilizing bioinformatics as a tool to identify the biosynthesis processes of bioactive compounds of edible and medicinal mushrooms
Paper ID : 1135-ICB10
Authors:
Mahnaz Mehrabi *
Pharmacy, pharmaceutical science, university of pécs, Hungary
Abstract:
There are a wide range of bioactive compounds in edible and medicinal mushrooms including polysaccharides (especially β-glucans), glycoproteins, peptides, terpenoids, sterols, and phenolic compounds. These compounds help prevent, treat, and recover from illness. Identification of factors affecting biosynthesis is very important for the production of bioactive compounds on industrial scales and pharmaceutical systems [1]. Therefore, bioinformatics methods can be used to analysis of the cellular and molecular structure of enzymes effective in biosynthesis processes and increase the production of bioactive compounds [2, 3]. The results of studies show that mineral ions such as zinc, copper, calcium, iron, and selenium can enhance the expression of genes that lead to the production of more bioactive compounds of edible and medicinal mushrooms, such as polysaccharides, triterpenoids and ganodric acids [4, 5]. The use of these findings could improve the biosynthesis of bioactive compounds and the performance of pharmaceutical biotechnology systems for the production of natural superfoods, dietary supplements and medicines [5].
Keywords:
Edible-medicinal mushrooms, Bioactive compounds, Biosynthesis, Dietary supplements, Natural medicines
Status : Paper Accepted (Poster Presentation)