1st International and 10th National Iranian Conference on Bioinformatics
Home Accepted Papers
Analysis of floral development related gene co-expression networks in Arabidopsis thaliana
Paper ID : 1342-ICB10
Authors:
Pouya Motienoparvar *1, Kaveh Kavousi2, mokhtar jalali Javaran3
1گروه بیوتکنولوژی کشاورزی، دانشکده کشاورزی، دانشگاه تربیت مدرس
2University of Tehran
3Tarbiat Modares University
Abstract:
The study of flower development is of great scientific, practical and applicable importance; because in this way, flowering control can be provided in plants. For example, it can be used in the production of male sterile plants to produce hybrid seeds. It should be noted that many regulatory genes are involved in the flowering process that have been identified previously. The interactions of genes involved with the formation of flower components are complex. In general, identifying the function of individual genes involved in flower development has not led to a complete and accurate understanding of the developmental process. In order to overcome this challenge, nine co-expression genes network of Arabidopsis taliana for two wild and three mutant ecotypes were reconstructed and analysed using WGCNA R package and cytoscape software platform. In the continuation of the research, the modules involved in trait control were identified and compared. After performing costumized RandomWalk algorithm on the co-expression networks, 10 key genes in addition to the deed genes used in this study were determined that has have important role in phase transition. Topological anf functional analysis of the networks indicated deeper changes during the phase transition phenomena in biochemical pathways (alternative passways were activated). In conclusion, focusing on the hormone alternative pathways could provide novel approaches to control flowering by genetic engineering.
Keywords:
systems biology; Arabidopsis thaliana; floral development; network analysis; community detection; flower differentiation.
Status : Paper Accepted (Poster Presentation)